RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
Malat1
RNA ID
RNA Type
lncrna
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
qRT-PCR; dual-luciferase reporter assay
Target
ZEB2
Pathway
NA
PubMed ID
Title
LncRNA MALAT1 facilities high glucose induced endothelial to mesenchymal transition and fibrosis via targeting miR-145/ZEB2 axis
Year
2019
Function
"Malat1 functions as a sponge RNA for miR-145 to derepress the expression of target gene zeb3, thereby inducing epithelial-mesenchymal transition (EMT) and fibrosis."